PRESENTATIONS 2014 |
| Opening - Definition of the course objectives - Paul-Henri Lambert, Director |
| SESSION 1 - THE MULTIFACETED NATURE OF VACCINOLOGY |
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Opening Lecture - Impact of Vaccination on disease epidemiology - Roy Anderson Access to cost-effective vaccination in GAVI countries and at global level - Stefano Malvoti Public and media perception of vaccination - David Salisbury Role of DC vaccine industry for meeting global needs - Suresh Jadhav Development and production of vaccines for global use: the role of vaccine industry - Luis Jodar |
| SESSION 2 - HOW VACCINES WORK |
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How are vaccine responses elicited? What a vaccinologist should know about the basic aspects of immunological responses a-B-cell responses. - Claire-Anne Siegrist Use and limitations of correlates of immunity in vaccinology - Pollard Immunological basis for responses to mucosal vaccines - Adam Finn Vaccines and Immunological memory (quizz and general discussion) - Claire-Anne Siegrist |
| SPECIAL LECTURE: |
| Vaccine-induced immunological memory - Rafi Ahmed |
| SESSION 3 - DECISION-MAKING IN VACCINE RESEARCH AND PRECLINICAL DEVELOPMENT |
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How do vaccines cause adverse events? - Neal Halsey Vaccines adjuvants - Martin Friede Narcolepsy - Hanna Nohynek From pre-clinical research to vaccine development - Georges Thiry Advances in vaccine and immunization technologies - Cristina Cassetti |
| SPECIAL LECTURES: NEW VACCINES IN DEVELOPMENT |
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HIV vaccines - Brigitte Autran TB vaccines - David Lewis Pertussis vaccines - Scott Halperin |
| SESSION 4 - ASSESSING VACCINES IN CLINICAL TRIALS (I) |
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Clinical Trials: an overview of issues to be considered - Myron Levine Lessons from pitfalls experienced in clinical trials and in the registration process - Luc Hessel Clinical trials: role of DSMB - Penny Heaton Assessing herd protection - John Clemens Introduction to statistical aspects of clinical trials (i) - Peter Smith |
| SESSION 5 - VACCINE SAFETY - ASSESSMENT OF ADVERSE EFFECTS |
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Lessons from previous adverse effects of vaccination and Assessment of causal relationships - Neal Halsey Immunology safety of vaccination (autoimmune and allergic diseases) - Paul-Henri Lambert Population-based post-licensure surveillance - Andrews Immunization safety in developping country vaccination programs - Philippe Duclos Risk communication an overview - Noni MacDonald |
| SESSION 6 - ASSESSING VACCINES IN CLINICAL TRIALS (II) |
| Introduction to stat. aspects of clinical trials (ii) - Peter Smith |
| SESSION 7 - ETHICAL ISSUES |
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Ethical considerations in clinical trials of vaccines - C. Slack Placebo versus comparator vaccine in clinical trials - Pieter Neels Ethics and regulation for comparative effectiveness research - Hanna Nohynek Ethics case malaria - Malaria case Conclusions of group work - C. Slack |
| SESSION 8.1 - INTRODUCING NEW VACCINES INTO VACCINATION PROGRAMMES (1) |
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Role of disease burden assessment in the decision-making process - Brad Gessner Health economics as a tool in analyzing Vaccine Policy Options - Mark Miller Challenges and solutions in making evidence-based national vaccination polices and recommendations - Ph. Duclos Understanding responses to polysaccharide and conjugate vaccines in infants and adults - D. Goldblatt Pneumococcal conjugate vaccines: overview - Dagan Pneumococcal vaccines: role of viral infections, ecological aspects, and issues related to adult vaccination (including protein vaccines) - Klugman The MenA-conjugate experience - Greenwood Present approaches towards group B and multivalent Meningococcal vaccines - Del Giudice |
| SESSION 8.2 - INTRODUCING NEW VACCINES INTO VACCINATION PROGRAMMES (2) |
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Understanding vaccine responses in the elderly - Richard Aspinall Influenza biology , new vaccines and vaccination strategies for different age groups - Kathy Neuzil Success and challenges with Rotavirus vaccines - Umesh Parashar |
| SPECIAL LECTURE: |
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The population biology of bacterial pathogens and its importance for vaccination strategies - Richard Moxon The challenge of malaria vaccines and of their potential introduction - Vasee Moorthy TUESDAY 20 MAY - Small Group Session |
| SESSION 9 - SELECTING APPROPRIATE VACCINATION STRATEGIES |
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Vaccination in pregnancy - Janet Englund Vaccination in early life - Claire-Anne Siegrist Vaccination schedule: Past, present and future - Is there some rationale? - Edwin Asturias History of Vaccines and Vaccination - Stanley Plotkin |
| PLOTKIN LECTURE: |
| systems biology and vaccination: Aderem |
| WEDNESDAY 21 MAY - Worshops |
| 1 - Vaccination-eRegistries - Kari johanssen 2 - Assessing Vaccines in DCs - Wilson-Beattie 3 - Nitags 4 - Clinical Vaccinology - Siegrist-Diana |
| Vaccination in immune-compromised individuals - Claire-Anne Siegrist |
| SPECIAL LECTURES: NEW VACCINES |
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CMV vaccines in development - Stanley Plotkin HPV vaccines - Margaret Stanley Prospects for dengue and JE vaccines - Hal Margolis Introduction of rabies vaccines into immunization programs - Deborah Briggs |
| ELIMINATION OR ERADICATION STRATEGIES? |
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Polio, focusing on new strategies - Roland Sutter Measles and rubella - Peter Strebel Introducing the ADVAC alumni network and the ADVAC community - Josette Najjar |